GSTM1, glutathione S-transferase mu 1, 2944

N. diseases: 627; N. variants: 9
Disease: Malignant transformation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.020 GeneticVariation phenotype BEFREE The unconditional logistic regression test revealed that patients with urinary bilharziasis and combined GSTM1 and T1 genes deletion are at a significant risk for malignant transformation (OR = 6.3, P < 0.05). 19117770 2010
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.020 GeneticVariation phenotype BEFREE We conclude that the GSTM1 null allele is not an endometriosis susceptibility allele, however, it may predispose endometriotic lesions to malignant transformation to endometrioid and clear cell ovarian cancer. 11159742 2001