|
Adenomatous Polyposis Coli
|
0.100 |
Biomarker
|
disease |
BEFREE |
GSTP1 and APC were hypermethylated in the majority of PCa tissue samples.
|
25738352 |
2015 |
|
Adenomatous Polyposis Coli
|
0.100 |
Biomarker
|
disease |
BEFREE |
Studies of the relationships of adenomatous polyposis coli (APC), glutathione-S-transferase P1 (GSTP1) and suppressor of the cytokine signalling 1 (SOCS1) promoter region methylation with the risk of hepatocellular carcinoma (HCC) have yielded inconsistent results.
|
25853848 |
2015 |
|
Adenomatous Polyposis Coli
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
The hazard ratio (HR) of prostate cancer mortality was 2.38 (95% confidence interval: 1.23-4.61) for APC methylation, and 2.92 (1.49-5.74) for GSTP1 methylation in NTAT.
|
23874531 |
2013 |
|
Adenomatous Polyposis Coli
|
0.100 |
Biomarker
|
disease |
BEFREE |
The methylation status of the genes of Adenomatous polyposis coli (APC) and glutathione-S-transferase-P1 (GSTP1) was analyzed by quantitative pyrosequencing.
|
22511308 |
2012 |
|
Adenomatous Polyposis Coli
|
0.100 |
Biomarker
|
disease |
BEFREE |
The primary outcome was the relative negative predictive value (NPV) of APC compared with GSTP1, and its 95% confidence interval (CI).
|
22077694 |
2012 |
|
Adenomatous Polyposis Coli
|
0.100 |
Biomarker
|
disease |
BEFREE |
Larger studies are necessary to investigate a potential correlation of GSTP1, RARβ2 and APC hypermethylation with tumor aggressiveness.
|
21116117 |
2010 |
|
Adenomatous Polyposis Coli
|
0.100 |
Biomarker
|
disease |
BEFREE |
Sera were analysed by methylation specific PCR (MethyLight PCR) for five genes: adenomatous polyposis coli (APC), ras association domain family protein 1A (RASSF1A), estrogen receptor 1 (ESR1), CDKN2A (p16) and glutathione s-transferase pi 1 (GSTP1).Beta actin (ACTB) served as control.
|
20696638 |
2010 |
|
Adenomatous Polyposis Coli
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
Results The two cohorts had different prevalences of methylation in APC (P = .047), GSTP1 (P = .002), and RUNX3 (P < .001).
|
19470943 |
2009 |
|
Adenomatous Polyposis Coli
|
0.100 |
Biomarker
|
disease |
BEFREE |
The methylation frequencies of the genes tested in NSCLC specimens were 52% for E-cadherin (CDH1), 41% for RAS association domain family protein (RASSF1A), 38% for fragile histidine triad (FHIT) and adenomatous polyposis coli (APC), 27% for retinoic acid receptor beta (RARbeta) and H-cadherin (CDH13), 20% for p16INK4A, 0.8% for O6-methylguanine-DNA-methyltransferase (MGMT), and 0% for glutathione S-transferase P1 (GSTP1).
|
15042681 |
2004 |
|
Adenomatous Polyposis Coli
|
0.100 |
Biomarker
|
disease |
BEFREE |
We obtained fresh-frozen sextant biopsies from 72 excised prostates and directly compared blinded histologic review and quantitative real-time methylation-specific PCR for hypermethylation of four genes, Tazarotene-induced gene 1 (TIG1), adenomatous polyposis coli (APC), retinoic acid receptor beta2 (RARbeta2), and glutathione S-transferase pi (GSTP1) to detect the presence of prostate cancer.
|
15328191 |
2004 |
|
Adenomatous Polyposis Coli
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
APC methylation and GSTP1 methylation in the primary tumor were both correlated with nonsquamous histology (P = 0.02 and P = 0.01 likelihood ratio respectively).
|
12684406 |
2003 |