GSTP1, glutathione S-transferase pi 1, 2950

N. diseases: 610; N. variants: 18
Disease: Malignant neoplasm of liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.030 Biomarker disease BEFREE The involvement of GSTP in the oxidative stress and in other human pathologies like cancer, liver and neurodegenerative diseases, and psychiatric disorders is also reported. 31357662 2019
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.030 AlteredExpression disease BEFREE Interrupting GSTP1 gene expression promoted liver cancer cell proliferation and increased the percentage of cells in S phase by decreasing levels of p21 and p27 and increasing p-Akt. 29507666 2018
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.030 PosttranslationalModification disease BEFREE Glutathione-S-transferase P1 (GSTP1) gene is commonly silenced by CpG island promoter hypermethylation in prostate, breast, and liver cancers. 21453686 2011