Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This meta-analysis provides new evidences that GSTP1 Ile105Val gene polymorphism contributes to EC susceptibility in Caucasians.
|
25280543 |
2015 |
Malignant neoplasm of esophagus
|
0.100 |
Biomarker
|
disease |
BEFREE |
Genetic polymorphisms of GSTM1, GSTT1 and GSTP1 in association with some environmental factors and their impact on esophageal cancer susceptibility were assessed in the Iranian population.
|
20409775 |
2010 |
Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These results suggest that p53 Arg72Pro polymorphism, but not GSTP1 Ile105Val, may contribute to esophageal cancer development, especially in Asian.
|
20827430 |
2010 |
Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A case-control study was performed in 135 EC patients and 195 healthy controls to analyze association of polymorphisms in glutathione S-transferase (GST) mu (GSTM1), GST theta (GSTT1), GST pi (GSTP1), GSTM3, Cytochrome P450 (CYP)1A1, and CYP2E1 genes with susceptibility to EC as well as their interaction with environmental factors such as smoking and high consumption of salted tea in Kashmir valley.
|
20661821 |
2010 |
Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer.
|
20540773 |
2010 |
Malignant neoplasm of esophagus
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
The conditional logistic regression analysis demonstrated that increased risk for esophageal cancer was associated with CpG island hypermethylation of promoter of GSTP1 gene.
|
20391126 |
2010 |
Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of GSTP1 and GSTT1, but not of CYP2A6, CYP2E1 or GSTM1, modify the risk for esophageal cancer in a western population.
|
17916905 |
2007 |
Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In patients with smoking habits, GSTM1 null and GSTP1 ile/ile genotype were at higher risk for esophageal cancer (OR 1.5; 95% CI=0.50-4.4 and OR 1.3; 95% CI=0.40-3.5), respectively.
|
16338071 |
2006 |
Malignant neoplasm of esophagus
|
0.100 |
Biomarker
|
disease |
BEFREE |
High gene expression of TS1, GSTP1, and ERCC1 are risk factors for survival in patients treated with trimodality therapy for esophageal cancer.
|
15788669 |
2005 |
Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The presence of the GSTP1 variant allele (Val) is associated with a poorer prognosis of esophageal cancer.
|
16000570 |
2005 |
Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
GSTM1, GSTT1, GSTP1 and CYP1A1 genetic polymorphisms and susceptibility to esophageal cancer in a French population: different pattern of squamous cell carcinoma and adenocarcinoma.
|
15526353 |
2004 |
Malignant neoplasm of esophagus
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Thus, we conducted a pilot case-control study to examine the association between CYP2E1, GSTM1, GSTT1, and GSTP1 genetic polymorphisms and esophageal cancer susceptibility.
|
9829710 |
1998 |