GSTP1, glutathione S-transferase pi 1, 2950

N. diseases: 610; N. variants: 18
Disease: Treatment related acute myeloid leukaemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1336735
Disease: Treatment related acute myeloid leukaemia
Treatment related acute myeloid leukaemia 		0.010 GeneticVariation disease BEFREE These data suggest that inheritance of at least one Val allele at GSTP1 codon 105 confers a significantly increased risk of developing t-AML after cytotoxic chemotherapy, but not after radiotherapy. 11553769 2001