Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
|
24362816 |
2014 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
Risks of Lynch syndrome cancers for MSH6 mutation carriers.
|
20028993 |
2010 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer.
|
20487569 |
2010 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients.
|
18301448 |
2008 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue.
|
14974087 |
2004 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.
|
15483016 |
2004 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
Familial endometrial cancer in female carriers of MSH6 germline mutations.
|
10508506 |
1999 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.
|
10348829 |
1999 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
CausalMutation
|
disease |
CLINVAR |
In vivo measurement of the volume of distribution of water in cerebral grey matter: effects on the calculation of regional cerebral blood flow.
|
1548301 |
1992 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Increasing recognition of the statistical burden posed by HNPCC (5 to 6 percent of all colorectal cancer) mandates that physicians have a better understanding of the genetics, natural history, and distinction between the hereditary site-specific variant (Lynch syndrome I) and the Cancer Family Syndrome (Lynch syndrome II).
|
3366037 |
1988 |
Colorectal cancer, hereditary nonpolyposis, type 1
|
0.110 |
GeneticVariation
|
disease |
CLINVAR |
|
|
|