GTF2I, general transcription factor IIi, 2969

N. diseases: 249; N. variants: 14
Disease: Pilocytic Astrocytoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334583
Disease: Pilocytic Astrocytoma
Pilocytic Astrocytoma 		0.020 Biomarker disease BEFREE Correction: A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma. 28880959 2019
CUI: C0334583
Disease: Pilocytic Astrocytoma
Pilocytic Astrocytoma 		0.020 Biomarker disease BEFREE Using a combined analysis of RNA sequencing and copy number variation data we identified a new BRAF fusion involving the 5' gene fusion partner GTF2I (7q11.23), not previously described in PA. 28448514 2017