GUCA2B, guanylate cyclase activator 2B, 2981

N. diseases: 38; N. variants: 2
Disease: Irritable bowel syndrome with constipation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4268639
Disease: Irritable bowel syndrome with constipation
Irritable bowel syndrome with constipation 		0.020 AlteredExpression disease BEFREE Similarly, fasting UGN levels were lower in patients with CIC and those with IBS-C compared with healthy subjects. 31318728 2019
CUI: C4268639
Disease: Irritable bowel syndrome with constipation
Irritable bowel syndrome with constipation 		0.020 Biomarker disease BEFREE Finally, the discussion within focuses on the importance of plecanatide in understanding the physiology of uroguanylin, the pathophysiology of IBS-C and the potential for development of uroguanylin and guanylin analogs. 29376436 2018