Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.430 Biomarker group BEFREE Notch signaling thus provides a constitutive drive on expression of the major nitric oxide receptor (GUCY1A3/GUCY1B3) in arteries from mice, rats, and humans, and this control mechanism is disturbed in hypertension. 28465505 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.430 GeneticVariation group BEFREE Disrupted nitric oxide signaling due to GUCY1A3 mutations increases risk for moyamoya disease, achalasia and hypertension. 26777256 2016
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.430 GeneticVariation group GWASCAT Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. 25249183 2015
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.430 GeneticVariation group BEFREE α1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders. 25373139 2014
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.430 Biomarker group CTD_human Gender-specific hypertension and responsiveness to nitric oxide in sGCalpha1 knockout mice. 18339647 2008
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.430 Biomarker group HPO