ICOS, inducible T cell costimulator, 29851

N. diseases: 193; N. variants: 9
Disease: Pneumonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.120 Biomarker disease BEFREE In the absence of ICOS, mice had improved survival in a pneumonia model with the methicillin-resistant Staphylococcus aureus (MRSA) strain USA300 and significant reductions in bacterial burden in a nonlethal acute pneumonia model. 29378030 2018
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.120 Biomarker disease BEFREE Here we showed that a lack of ICOS on murine ILC2s and blocking the ICOS:ICOS-ligand interaction in human ILC2s reduced AHR and lung inflammation. 25769613 2015
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.120 Biomarker disease HPO