ICOS, inducible T cell costimulator, 29851

N. diseases: 193; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3662483
Disease: Allergic sensitization
Allergic sensitization
0.020 GeneticVariation disease BEFREE Also four other ICOS variants at putative binding sites for transcription factors showed no association with atopic dermatitis, asthma, allergic sensitization and allergic rhinitis. 19175887 2009
CUI: C3662483
Disease: Allergic sensitization
Allergic sensitization
0.020 Biomarker disease BEFREE Overall, these data demonstrate that ICOS is a susceptibility gene for allergic sensitization, perhaps through the promotion of Th2 differentiation. 16081771 2005