RMC1, regulator of MON1-CCZ1, 29919

N. diseases: 110; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.030 AlteredExpression disease BEFREE Clinically, serum MIC1 levels were significantly higher in PCa patients than in healthy controls, and higher levels were associated with higher pathological grade and obesity. 24344250 2014
CUI: C0028754
Disease: Obesity
Obesity
0.030 GeneticVariation disease BEFREE We explored whether alterations in MIC-1 levels contribute to metabolic disturbances in patients with obesity and/or obesity and type 2 diabetes mellitus (T2DM). 19515791 2009
CUI: C0028754
Disease: Obesity
Obesity
0.030 Biomarker disease BEFREE Thus, MIC-1 is a newly defined central regulator of appetite and a potential target for the treatment of both cancer anorexia and weight loss, as well as of obesity. 17982462 2007