Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.030 AlteredExpression disease BEFREE In summary, miR-211-5p promotes chondrocyte differentiation by negatively regulating Fibulin-4 expression, and represses the expression of pro-inflammatory cytokines and proteinases responsible for cartilage matrix degradation in OA. miR-211-5p may serve as a promising target for OA treatment. 31396630 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.030 Biomarker disease BEFREE Our study provides evidence of a previously unknown link between Fibulin-4 and the canonical Wnt/β-catenin pathway that may contribute to our understanding of the molecular mechanisms of OA. 28238906 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.030 AlteredExpression disease BEFREE Taken together, fibulin-4, expressed in chondrocytes and recognized as an autoantigen mainly in OA rather than in RA, may play pathogenic roles in OA. 16493080 2006
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.030 AlteredExpression disease LHGDN Taken together, fibulin-4, expressed in chondrocytes and recognized as an autoantigen mainly in OA rather than in RA, may play pathogenic roles in OA. 16493080 2006