GZMB, granzyme B, 3002

N. diseases: 290; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
0.020 Biomarker disease BEFREE Primary Tr1 cells from metastatic melanoma eliminate tumor-promoting macrophages through granzyme B- and perforin-dependent mechanisms. 28378637 2017
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
0.020 AlteredExpression disease BEFREE Increased expression of perforin and granzyme B genes in patients with metastatic melanoma treated with recombinant interleukin-2. 8044827 1994