H1-0, H1.0 linker histone, 3005

N. diseases: 36; N. variants: 1
Disease: Ataxia Telangiectasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004135
Disease: Ataxia Telangiectasia
Ataxia Telangiectasia 		0.020 Biomarker disease BEFREE We recently demonstrated that linker histone H1, which is thought to have a fundamental role in higher-order chromatin structure, becomes transiently dephosphorylated after ionizing radiation (IR) in a mutated ataxia telangiectasia (ATM) dependent manner. 11059758 2000
CUI: C0004135
Disease: Ataxia Telangiectasia
Ataxia Telangiectasia 		0.020 AlteredExpression disease BEFREE Cloned genomic DNA for human histone H1, H3 and H4 genes has been used to determine the effects of gamma-radiation on histone mRNA levels and synthesis in ataxia-telangiectasia cells. 3807898 1987