H1-0, H1.0 linker histone, 3005

N. diseases: 36; N. variants: 1
Disease: Leukemia, B-Cell ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2004493
Disease: Leukemia, B-Cell
Leukemia, B-Cell 		0.010 AlteredExpression disease BEFREE Using serial histone H1-deletion mutant cells established from the chicken B-cell leukemia line DT40, we found that apoptotic chromatin condensation was decreased in relation to histone H1 protein level and that the chromatin in nuclei prepared from the live null mutant cells had a high accessibility of DNases and transposase. 30879765 2019