H2AX, H2A.X variant histone, 3014

N. diseases: 212; N. variants: 6
Disease: Werner Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0043119
Disease: Werner Syndrome
Werner Syndrome 		0.020 Biomarker disease BEFREE The rates of recruitment of DSB repair proteins to gamma-H2AX foci correlated inversely with age for both normal and Werner syndrome donors, perhaps due in part to the slower growth of gamma-H2AX foci in older donors. 18005250 2008
CUI: C0043119
Disease: Werner Syndrome
Werner Syndrome 		0.020 Biomarker disease LHGDN Consistent with this, gamma H2AX colocalizes with Nbs1 in WS cells but not with WRN in NBS cells. 15733840 2005