DisGeNET - a database of gene-disease associations

H3-3A, H3.3 histone A, 3020

N. diseases: 134; N. variants: 4

Disease: GLIOMA SUSCEPTIBILITY 1 ×

The Variant filter does not apply in GDA tabs

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C2750850
Disease:	GLIOMA SUSCEPTIBILITY 1

GLIOMA SUSCEPTIBILITY 1

0.300

GeneticVariation

phenotype

UNIPROT

Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.

23539269

2013

CUI:	C2750850
Disease:	GLIOMA SUSCEPTIBILITY 1

GLIOMA SUSCEPTIBILITY 1

0.300

GeneticVariation

phenotype

UNIPROT

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.

22286061

2012

CUI:	C2750850
Disease:	GLIOMA SUSCEPTIBILITY 1

GLIOMA SUSCEPTIBILITY 1

0.300

GeneticVariation

phenotype

UNIPROT

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.

22286216

2012