HABP2, hyaluronan binding protein 2, 3026

N. diseases: 88; N. variants: 9
Disease: Thyroid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.240 GeneticVariation disease BEFREE Indeed, affected individuals not carrying HABP2<sup>G534E</sup> were identified, and the variant was present also in members without thyroid cancer. 28222214 2017
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.240 GeneticVariation disease BEFREE Heterozygosity for the G534E variant in HABP2 was present in 7.6 % of Busselton Health Study participants (N = 4634, unknown disease status) and 9.3 % of TwinsUK participants (N = 1195, no history of thyroid cancer). 27530615 2016
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.240 GeneticVariation disease BEFREE These results are consistent with HABP2 G534E being a susceptibility gene in a subgroup of FNMTC, providing important diagnostic implications for this hereditary thyroid cancer. 26832773 2016
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.240 GeneticVariation disease BEFREE Here, we report a germline variant of HABP2 in seven affected members of a kindred with familial nonmedullary thyroid cancer and in 4.7% of 423 patients with thyroid cancer. 26222560 2015
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.240 Biomarker disease RGD Lac color inhibits development of rat thyroid carcinomas through targeting activation of plasma hyaluronan-binding protein. 22715430 2012