HABP2, hyaluronan binding protein 2, 3026

N. diseases: 88; N. variants: 9
Disease: Fibrosis, Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.040 Biomarker disease BEFREE Factor VII (FVII) activating protease (FSAP) is a circulating serine protease that is likely to be involved in a number of disease conditions such as stroke, atherosclerosis, liver fibrosis, thrombosis and cancer. 28726978 2017
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.040 AlteredExpression disease BEFREE Liver fibrosis is associated with a decrease in FSAP expression but, to date, nothing is known about how this might be regulated. 27462075 2016
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.040 AlteredExpression disease BEFREE Lower FSAP expression is associated with enhanced liver fibrosis and inflammation in patients with chronic hepatic disorders and murine experimental liver injury. 22989567 2013
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.040 GeneticVariation disease BEFREE The G534E variant of FSAP is a risk locus for HCV-induced liver fibrosis and cirrhosis by determining PDGF-BB-mediated hepatic stellate cell proliferation through a single amino acid substitution in FSAP. 19105210 2009