HBA2, hemoglobin subunit alpha 2, 3040

N. diseases: 182; N. variants: 34
Disease: Thalassemia Minor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085578
Disease: Thalassemia Minor
Thalassemia Minor 		0.340 GeneticVariation disease BEFREE Moreover, a deletion of approximately 19.3 kb of DNA with α-globin genes (<sup>_ _SEA</sup>) was associated with thalassemia minor in the family. 28827396 2017
CUI: C0085578
Disease: Thalassemia Minor
Thalassemia Minor 		0.340 GeneticVariation disease BEFREE Only 4.4% of suspected cases with lower than normal RBC indices (mean corpuscular volume <80 fl and mean corpuscular Hb <27 pg) and HbA2 (<3.5%) were diagnosed with thalassaemia minor. 26992783 2017
CUI: C0085578
Disease: Thalassemia Minor
Thalassemia Minor 		0.340 Biomarker disease BEFREE The major clinical significance of HbA2' is that failure to detect it might lead to failure to recognize beta-thalassaemia minor. 18665832 2008
CUI: C0085578
Disease: Thalassemia Minor
Thalassemia Minor 		0.340 Biomarker disease CTD_human Interaction of hemoglobin and copper nanoparticles: implications in hemoglobinopathy. 17292142 2006
CUI: C0085578
Disease: Thalassemia Minor
Thalassemia Minor 		0.340 GeneticVariation disease BEFREE In this paper we report that the combination of a triplicated alpha globin locus with heterozygous beta-thalassaemia produces a clinical phenotype of thalassaemia intermedia in five Italian subjects from four unrelated families, while in two other cases the phenotype was thalassaemia minor. 3593644 1987