SERPIND1, serpin family D member 1, 3053

N. diseases: 60; N. variants: 5
Disease: Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.030 AlteredExpression disease BEFREE Here, the question was addressed whether the small leucine-rich proteoglycan biglycan acts as an endogenous thrombin inhibitor in atherosclerosis through activation of heparin cofactor II. 27034473 2016
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.030 Biomarker disease BEFREE This patient led us to conduct clinical studies to examine the role of HCII against atherosclerosis. 19729870 2009
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.030 AlteredExpression disease BEFREE Heparin cofactor II (HCII) is a hepatic serpin with significant antithrombin activity that has been implicated in coagulation, inflammation, atherosclerosis, and wound repair. 15337701 2004