HCFC1, host cell factor C1, 3054

N. diseases: 100; N. variants: 7
Disease: Herpes Simplex Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.040 Biomarker group BEFREE The cellular transcriptional coactivator HCF-1 is required for initiation of herpes simplex virus (HSV) lytic infection and for reactivation from latency in sensory neurons. 28407486 2017
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.040 Biomarker group LHGDN Sequence variants in host cell factor C1 are associated with Ménière's disease. 18520591 2008
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.040 Biomarker group BEFREE Originally identified as an essential component of the herpes simplex virus immediate early (IE) gene enhancer complex, the transcriptional coactivator host cell factor-1 (HCF-1) has been implicated in a broad range of cellular regulatory circuits. 17578910 2007
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.040 Biomarker group BEFREE A novel function for human factor C1 (HCF-1), a host protein required for herpes simplex virus infection, in pre-mRNA splicing. 12456665 2002