HDAC1, histone deacetylase 1, 3065

N. diseases: 277; N. variants: 1
Disease: Neuralgia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.030 AlteredExpression phenotype BEFREE HDAC2, but not HDAC1, regulates Kv1.2 expression to mediate neuropathic pain in CCI rats. 31022463 2019
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.030 Biomarker phenotype BEFREE The HDAC1/c-JUN complex is essential in the promotion of nerve injury-induced neuropathic pain through JNK signaling. 29477655 2018
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.030 Biomarker phenotype BEFREE These data illustrate the antihyperalgesic efficacy of LG325 indicating that selectively targeting HDAC1 could have promising therapeutic potential for neuropathic pain management. 28821396 2017