HDAC1, histone deacetylase 1, 3065

N. diseases: 277; N. variants: 1
Disease: Osteoporosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.020 Biomarker disease BEFREE Puerarin alleviates streptozotocin (STZ)-induced osteoporosis in rats through suppressing inflammation and apoptosis via HDAC1/HDAC3 signaling. 31054509 2019
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.020 Biomarker disease BEFREE More importantly, we found an inhibitory role of Hdac1 in regulating bone formation in response to hindlimb unloading in mice, and pretreatment with an HDAC1 inhibitor partly rescued the osteoporosis caused by mechanical unloading. 27171263 2016