HDAC1, histone deacetylase 1, 3065

N. diseases: 277; N. variants: 1
Disease: Hepatocarcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.030 Biomarker disease BEFREE However, molecular mechanisms of HDAC1 action in liver carcinogenesis are largely unknown. 23621261 2013
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.030 AlteredExpression disease BEFREE Recently, HDAC1 has been reported to be overexpressed in hepatocellular carcinoma (HCC), but its biological roles in hepatocarcinogenesis remain to be elucidated. 22496786 2012
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis 		0.030 Biomarker disease BEFREE Mutations and alterations of the IGF-axis as well as of chromosome 1p34, where the genes for histone deacetylase 1 (HDAC1) and transforming growth factor beta receptor interacting protein-1 (TRIP-1) map, are frequent events in hepatocarcinogenesis. 10601571 2000