HELLS, helicase, lymphoid specific, 3070

N. diseases: 84; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 Biomarker disease BEFREE GINS4 facilitates lung cancer progression by promoting key characteristics of tumor potential, and LSH epigenetically interacts with and stabilizes GINS4 transcripts. 31253190 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 AlteredExpression disease BEFREE This study demonstrates that BaP promotes proliferation by activation of AhR, which promotes SMARCA6 expression, and may identify new diagnostic and therapeutic targets in lung cancer. 30094095 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 Biomarker disease BEFREE Finally, we demonstrated that LSH functioned as an oncogene in lung cancer <i>in vitro</i> and <i>in vivo</i>. 28900510 2017