CFH, complement factor H, 3075

N. diseases: 225; N. variants: 112
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017665
Disease: Membranous glomerulonephritis
Membranous glomerulonephritis
0.210 Biomarker disease LHGDN Complement factor H contributes to the control mechanism of in situ complement activation and prevents renal damage in idiopathic membranous nephropathy. 15331938 2005
CUI: C0017665
Disease: Membranous glomerulonephritis
Membranous glomerulonephritis
0.210 Biomarker disease RGD As modeled both in vitro and in vivo in the rat, factor H is up-regulated in membranous nephropathy. 12911541 2003
CUI: C0017665
Disease: Membranous glomerulonephritis
Membranous glomerulonephritis
0.210 Biomarker disease RGD A polymerase chain reaction (PCR)-based strategy was utilized to clone the full-length cDNA of GEC factor H. The relative quantity of factor H mRNA was measured by quantitative reverse transcription (RT)-PCR in cultured GEC exposed to complement activation and in the passive Heymann nephritis (PHN) model of membranous nephropathy. 12911541 2003