CFH, complement factor H, 3075

N. diseases: 393; N. variants: 150
Disease: Coronary Artery Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE The clinical implications for CAD and a better understanding of the functional basis for the association of CFH and MPO variants with circulating MPO levels require further study. 23620142 2013
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE Complement factor H Y402H gene polymorphism and coronary heart disease susceptibility: a meta-analysis. 20127520 2011
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals. 20708732 2010
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 AlteredExpression disease BEFREE There was no difference of plasma CFH levels between CAD group and controls. 18604638 2009
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE We investigated the association of polymorphisms of the CFH gene in two large-scale studies on CAD and myocardial infarction (MI). 17396242 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE The aim of the present study was to test for an association between the CFH-Y402H variant and MI in a large case-control sample with a familial background for CAD (coronary artery disease). 17472578 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE In this family-based study, we found no association between the CFH gene and early-onset coronary heart disease. 17877809 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE Complement factor H (Y402H) polymorphism and risk of coronary heart disease in US men and women. 17483111 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE The overall association of the CFH genotype with CAD was not statistically significant (P=.08). 17352366 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation disease BEFREE A total of 5,520 participants without history of coronary heart disease was genotyped for the Tyr402His polymorphism of the CFH gene. 16630992 2006