HGF, hepatocyte growth factor, 3082

N. diseases: 671; N. variants: 22
Disease: Morphologically altered structure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1260954
Disease: Morphologically altered structure
Morphologically altered structure 		0.010 AlteredExpression disease BEFREE Down-regulating PAX3-FKHR caused (a) tumor cells to accumulate in the G1 phase, inhibiting the rate of cellular proliferation, (b) a reduction in the levels of the MET, reducing cell motility stimulated by HGF, and (c) induction of the myogenic differentiation gene, myogenin, and muscle differentiation (morphologic change and the expression of muscle specific proteins, desmin, and myosin heavy chain). 18022385 2008