CXXC1, CXXC finger protein 1, 30827

N. diseases: 15; N. variants: 0
Disease: Autoimmune Diseases ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.010 AlteredExpression group BEFREE Therefore, these data highlight that Cxxc1 as a key regulator governs the balance between T<sub>H</sub>17 and T<sub>reg</sub> cells by controlling the expression of IL-6Rα, which affects IL-6/STAT3 signaling and has an impact on T<sub>H</sub>17-related autoimmune diseases. 31633019 2019