NRG1, neuregulin 1, 3084

N. diseases: 304; N. variants: 65
Disease: Major Depressive Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 Biomarker disease BEFREE Because both neuregulin-1 and ErbB4 are susceptibility genes of schizophrenia and major depression, our study contributes to a better understanding of these disorders.VIDEO ABSTRACT. 29628188 2018
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 GeneticVariation disease BEFREE BDNF and NRG1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression. 29310728 2018
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 Biomarker disease BEFREE To further investigate whether NRG1 is a shared risk gene for major depressive disorder, bipolar disorder as well as schizophrenia, we performed an association study among 1,248 schizophrenia cases, 1,056 major depression cases, 1,344 bipolar disorder cases, and 1,248 controls. 26888291 2016
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 GeneticVariation disease GWASCAT Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs. 25944848 2015
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 GeneticVariation disease BEFREE We observed however an association of rs6994992 with NRG1 type IV expression in DLPFC and a significantly decreased expression in MDD compared to controls. 21745728 2011
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 Biomarker disease BEFREE Our findings do not provide evidence that NRG1 plays a role in MDD or that this gene explains part of the genetic overlap with BPD. 19367584 2010