NRG1, neuregulin 1, 3084

N. diseases: 304; N. variants: 65
Disease: Symptomatic epilepsy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1406659
Disease: Symptomatic epilepsy
Symptomatic epilepsy 		0.010 Biomarker disease BEFREE Our study revealed a critical role of the NRG1-ErbB4 signaling pathway in symptomatic epilepsy, which is different from that in primary epilepsy, and we propose that the NRG1-ErbB4 signaling may act as a homeostasis modulator that protects the brain from aggravation of epileptiform activity. 28273943 2017