|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The correlation test between allelic frequency and the occurrence of autoimmune diseases indicated a significant correlation between the HLA-B*08 allele and rheumatoid arthritis.
|
30217207 |
2018 |
|
Rheumatoid Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Patients diagnosed with rheumatoid arthritis (RA), Ankylosing spondylitis (AS), Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), systemic sclerosis (SSc), dermatomyositis (DM), or polymyositis were included.
|
28508950 |
2018 |
|
Rheumatoid Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Ankylosing spondylitis (AS) is a common type of rheumatoid disease, which has recently been demonstrated to be associated with the expression of matrix metalloproteinase (MMP)-2.
|
29435070 |
2018 |
|
Rheumatoid Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Erratum: Correction of Phrase: Risk Factors Associated with Estimated Glomerular Filtration Rate in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis after Treatment with Biological Disease Modifying Anti-Rheumatic Drugs.
|
30093849 |
2018 |
|
Rheumatoid Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Corrigendum to "Serum Sclerostin Levels in Patients with Ankylosing Spondylitis and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis".
|
29181394 |
2017 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Flare was defined as change in 28 Joint Disease Activity Score (∆DAS28) ≥1.2 (RA/PsA) or Ankylosing Spondylitis Disease Activity Score (∆ASDAS) ≥1.3 (AxSpA).
|
28473425 |
2017 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
We tested the association between having any child with alleles encoding amino acids (AAs) associated with RA including the 'shared epitope' (SE) and DERAA AA sequences at positions 70-74; AA valine, lysine and alanine at positions 11, 71 and 74 of HLA-DRB1; aspartic acid at position 9 of HLA-B and phenylalanine at position 9 of DPB1.
|
28391248 |
2017 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Conditional and haplotype analyses identified that three amino acid positions (11, 71 and 74) in HLA-DRβ1 and single-amino-acid polymorphisms in HLA-B (at position 9) and HLA-DPβ1 (at position 9), which are all located in peptide-binding grooves, almost completely explain the MHC association to rheumatoid arthritis risk.
|
22286218 |
2012 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
To examine the possible association of some marker of Caucasian MHC genes and susceptibility to rheumatoid arthritis (RA) in African Americans, we studied extended MHC haplotypes (HLA-B, complement and DR) in a sample of 18 African American and Afro-Caribbean probands with RA, their first degree relatives and in 15 non-RA families.
|
9395559 |
1996 |
|
Rheumatoid Arthritis
|
0.200 |
Biomarker
|
disease |
BEFREE |
The results suggest that a specific combination of antigens in the same haplotype (for instance between HLA-B and HLA-DR) could contribute to increasing the genetic susceptibility to develop RA.
|
7842529 |
1995 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The restriction fragment length polymorphism of the two human HLA-B-associated transcripts (BATs) genes, BAT1 and BAT2, identifying polymorphic bands of 12, 8, 2.5, and 1.1 kb, and at 3.3, 2.7, 2.3, and 0.9 kb, respectively, was investigated in patients with primary biliary cirrhosis (PBC), systemic lupus erythematosus (SLE), pauciarticular juvenile rheumatoid arthritis (P-JRA), rheumatoid arthritis (RA), and primary Sjögren's syndrome (pSS), and in healthy Danes.
|
1672123 |
1991 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Data from HLA genotyped RA and normal families allowed an examination of haplotype combinations of HLA-B antigens and DR4/Dw types to be made.
|
2565608 |
1989 |
|
Rheumatoid Arthritis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Linkage analysis suggested that susceptibility to RA in this family was influenced by a dominant gene located centromeric to HLA-B.
|
6214529 |
1982 |