Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The chicken MHC-B is known to be highly associated with resistance to numerous diseases caused by viruses, bacteria, and parasitic pathogens.
|
31376352 |
2019 |
Virus Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Here, we showed that infection of several cell types, including epithelial A549 cells, with a panel of IAV and IBV viruses downregulated the surface MHC-I expression on IAV/IBV-infected cells during the late stages of influenza virus infection <i>in vitro</i>.
|
31191533 |
2019 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
These observations led us to hypothesize that some variants of HLA-C, in the presence of viral infections, could determine a greater release and accumulation of β<sub>2</sub>m, which in turn, may be involved in triggering and/or sustaining neuroinflammation.ADC is the most severe form of HAND.
|
30298049 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
In addition, the findings provide further evidence for the importance of HLA-C-restricted T-cells in the control of chronic viral infection.
|
29312307 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The physiological role of activating KIR or Ly49 receptors that recognize self-MHC class I during immune response to viral infections is unknown.
|
27438766 |
2016 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
HLA-C is unique among the classical MHC class I molecules for its role in the control of viral infections and recognition of abnormal or missing self.
|
25083782 |
2014 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Thus, HLA-C restricted T cells might play an important role in various viral infections.
|
24227846 |
2014 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Protective effect of HLA-DRB1 11 and predisposition of HLA-C 04 in the development of severe liver damage in Brazilian patients with chronic hepatitis C virus infection.
|
22803655 |
2012 |
Virus Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In conclusion, our data identify a new immunomodulatory protein, pUL56, involved in MHC-I downregulation which is unable to perform its function outside the context of viral infection.
|
22278226 |
2012 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study.
|
21931540 |
2011 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
As an in vivo model for studying human MHC (HLA) class I-restricted CTL responses to viral infection, we established a series of HLA Tg mice expressing HLA-A2, -B7 or -B27 human/mouse hybrid genes on a background deficient for H2 class I (Tg HLA(hyb)/H2 class I DKO).
|
16099553 |
2005 |
Virus Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In chronic hepatitis C virus infection MHC-I expression in the liver seems to relate to viral-genotype.
|
15288483 |
2004 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The development of peptide-MHC tetrameric complexes heralds a new era in the study of antigen-specific T cells and their role in viral infections.
|
14871536 |
2004 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
NK cells mediate spontaneous non-MHC-restricted killing of a wide variety of target cells without prior sensitization and appear to be involved in initial protection against certain viral infections.
|
1672164 |
1991 |