HMGA1, high mobility group AT-hook 1, 3159

N. diseases: 206; N. variants: 5
Disease: Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes 		0.030 Biomarker disease BEFREE Consistently, lack of HMGA1 causes insulin resistance and diabetes in humans and mice, while variations in the <i>HMGA1</i> gene are associated with the risk of type 2 diabetes and metabolic syndrome, two highly prevalent diseases that share insulin resistance as a common pathogenetic mechanism. 30034366 2018
CUI: C0011847
Disease: Diabetes
Diabetes 		0.030 GeneticVariation disease BEFREE We used logistic regression to test association of the HMGA1 IVS5-13insC and diabetes, adjusted for age, gender, body mass index, and percentage European, African, and Native American ancestry. 23302499 2013
CUI: C0011847
Disease: Diabetes
Diabetes 		0.030 Biomarker disease BEFREE Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice. 15924147 2005