HMGA1, high mobility group AT-hook 1, 3159

N. diseases: 206; N. variants: 5
Disease: Endotoxemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0376618
Disease: Endotoxemia
Endotoxemia 		0.020 Biomarker phenotype BEFREE These mice allowed us to specifically study the importance of HMGA1 not only during a purely pro-inflammatory insult of endotoxemia, but also during microbial sepsis induced by implantation of a bacterial-laden fibrin clot into the peritoneum. 29975792 2018
CUI: C0376618
Disease: Endotoxemia
Endotoxemia 		0.020 AlteredExpression phenotype BEFREE To determine whether MGBs exert beneficial effects during endotoxemia through attenuating tissue inflammation via interfering with HMGA1-DNA binding and modulating expression of adhesion molecules. 20498830 2010