HMGA1, high mobility group AT-hook 1, 3159

N. diseases: 206; N. variants: 5
Disease: Glioblastoma Multiforme ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 AlteredExpression disease BEFREE HMGA1 negatively regulates NUMB expression at transcriptional and post transcriptional level in glioblastoma stem cells. 31116627 2019
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 Biomarker disease BEFREE These results demonstrate a pivotal role of HMGA1 in cancer stem cell gliomagenesis and endorse HMGA1 as a suitable target for CSC-specific GBM therapy. 27486901 2016
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 AlteredExpression disease BEFREE Epigenetic modulation of a miR-296-5p:HMGA1 axis regulates Sox2 expression and glioblastoma stem cells. 26898758 2016
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 Biomarker disease BEFREE These findings suggest that HMGA1 potentially plays an important role in the treatment of GBM. 26092597 2015
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 AlteredExpression disease BEFREE Real-time quantitative PCR results, also, were indicative of HMGA1 overexpression in glioblastoma multiforme compared with WHO grade II (P = 0.043) and WHO grade III (P = 0.031) gliomas. 21984063 2012
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 Biomarker disease BEFREE We conclude that HMGA1 may be a potential biomarker and rational therapeutic target for glioblastoma and GSC. 21300033 2011