HMOX1, heme oxygenase 1, 3162

N. diseases: 666; N. variants: 9
Disease: Acute pancreatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.050 Biomarker disease BEFREE Here, we explore the mechanisms based on our previous study associated with the deregulation of heme oxygenase-1 (HO-1) and development of severe acute pancreatitis. 31210657 2019
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.050 Biomarker disease BEFREE In this study, we investigated the regulatory mechanisms of HO-1 during AP using desoxo-narchinol-A (DN), the natural compound inducing HO-1 in the pancreas. 30738992 2019
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.050 Biomarker disease BEFREE Protective effects of heme oxygenase-1 against severe acute pancreatitis via inhibition of tumor necrosis factor-α and augmentation of interleukin-10. 28836936 2017
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.050 AlteredExpression disease BEFREE In this study, we hypothesized that the expression of heme oxygenase-1 determined by the number of guanidinium thiocyanate (GT) repeats can influence the occurrence of acute pancreatitis. 25036905 2014
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.050 GeneticVariation disease BEFREE In conclusion, AP leads to reversible PBMC HO-1 upregulation that is associated with clinical improvement and involves primarily monocytes. 20966033 2011