|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our study indicates that both the HO-1(GT)n repeat length polymorphism and the T(-413)A SNP are associated with decreased risk of CHD.
|
27825138 |
2016 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We analyzed the allelic frequencies of guanosine thymidine dinucleotide repeats in the heme oxygenase-1 gene promoter in 386 patients with coronary artery disease recruited from January 1999 to July 2001 and followed until August 31, 2012.
|
24762402 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
HMOX1 gene promoter polymorphism is not associated with coronary artery disease in Koreans.
|
25187885 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between heme oxygenase 1 gene promoter polymorphisms and susceptibility to coronary artery disease: a HuGE review and meta-analysis.
|
24670375 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Shorter GT repeats in the heme oxygenase-1 gene promoter are associated with a lower severity score in coronary artery disease.
|
23602216 |
2013 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The prediction of coronary artery disease based on non-invasive examinations and heme oxygenase 1 polymorphism versus virtual histology.
|
23293173 |
2013 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
S/S genotype in HO-1 gene promoter is associated with a lower risk of CHD in subjects with higher levels of OS, because under conditions of high OS, the S/S genotype has higher levels of HO-1, an antioxidant.
|
22120665 |
2012 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Although a direct association between HO-1, vulnerable plaque development, and clinical outcome is for now missing, the correlations that have been reported for HO-1 and coronary artery disease point to a possible link.
|
20656217 |
2010 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A functional GT-repeat polymorphism in the heme oxygenase-1 (HO-1) gene promoter is inversely correlated with the development of coronary artery disease and restenosis after clinical angioplasty.
|
20708634 |
2010 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A functional GT-repeat polymorphism in the HO-1 gene promoter was inversely correlated to the development of coronary artery disease in diabetics and development of restenosis following angioplasty in patients.
|
20796278 |
2010 |
|
Coronary heart disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The protein expression of heme oxygenase-1, hypoxia inducible factor-1alpha, and ubiquitin was significantly stronger in patients with coronary heart disease than in controls, and the expression levels increased with the severity of the disease.
|
19676145 |
2009 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A (GT)n dinucleotide repeat and a -413A>T single nucleotide polymorphism have been reported in the promoter region of HMOX1 to both influence the occurrence of coronary artery disease and myocardial infarction.
|
19389234 |
2009 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Serum bilirubin and ferritin levels link heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients.
|
18443197 |
2008 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The HO-1 gene GT dinucleotide repeat promoter polymorphism and HO-1 +99G/C variant were evaluated in 199 patients with coronary artery disease after coronary stent implantation and control angiography at 6 months after the intervention.
|
16020495 |
2005 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Although potentially beneficial effects of the short HO-1 allele on lipid profile and serum bilirubin were observed, in contrast to Orientals, the HO-1 genotype was not associated with coronary artery disease in Caucasians.
|
14691581 |
2004 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Intragraft heme oxygenase-1 and coronary artery disease after heart transplantation.
|
15589739 |
2004 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors.
|
12377749 |
2002 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients.
|
12136229 |
2002 |