HMOX1, heme oxygenase 1, 3162

N. diseases: 510; N. variants: 6
Disease: Congestive heart failure ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.560 Biomarker disease BEFREE It was also reported that HO-1 induction improved the cardiac function and postinfarction survival in animal models of heart failure or myocardial infarction. 31344980 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.560 GeneticVariation disease BEFREE The number of HO-1 promoter GT(n) polymorphism is increased in both IDCM and CRF children with HF, but is unrelated to plasma markers of different pathological processes. 25822459 2015
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.560 Biomarker disease BEFREE The role of HO-1 in heart failure is not known, particularly in the setting of pressure overload. 24813593 2015
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.560 AlteredExpression disease BEFREE Moreover, myocyte-specific HO-1 overexpression in HF promoted tissue neovascularization and ameliorated myocardial p53 expression (2-fold reduction) and apoptosis. 20404253 2010
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.560 Biomarker disease BEFREE These results suggest that preemptive HO-1 gene delivery may be useful as a therapeutic strategy to reduce post-MI LV remodeling and heart failure. 17322421 2007
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.560 GeneticVariation disease BEFREE Functional heme oxygenase-1 promoter polymorphism in relation to heart failure and cardiac transplantation. 15797755 2005