HMOX1, heme oxygenase 1, 3162

N. diseases: 666; N. variants: 9
Disease: Postinfarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0857175
Disease: Postinfarction
Postinfarction 		0.040 Biomarker disease BEFREE It was also reported that HO-1 induction improved the cardiac function and postinfarction survival in animal models of heart failure or myocardial infarction. 31344980 2019
CUI: C0857175
Disease: Postinfarction
Postinfarction 		0.040 Biomarker disease BEFREE Compared with nontransgenic mice, HO-1 transgenic HF mice exhibited significantly (P<0.05) improved postinfarction survival (94% versus 57%) and less LV dilatation (end-diastolic volume, 46+/-8 versus 85+/-32 microL), mechanical dysfunction (ejection fraction, 65+/-9% versus 49+/-16%), hypertrophy (LV/tibia length 4.4+/-0.4 versus 5.2+/-0.6 mg/mm), interstitial fibrosis (11.2+/-3.1% versus 18.5+/-3.5%), and oxidative stress (3-fold reduction in tissue malondialdehyde). 20404253 2010
CUI: C0857175
Disease: Postinfarction
Postinfarction 		0.040 Biomarker disease BEFREE However, the effect of preemptive HO-1 gene delivery on long-term survival and prevention of postinfarction heart failure has not been determined. 17322421 2007
CUI: C0857175
Disease: Postinfarction
Postinfarction 		0.040 Biomarker disease BEFREE However, the effect of HO-1 gene delivery on postinfarction recovery has not been investigated. 16449792 2006