HMOX1, heme oxygenase 1, 3162

N. diseases: 666; N. variants: 9
Disease: Histiocytosis haematophagic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0876991
Disease: Histiocytosis haematophagic
Histiocytosis haematophagic 		0.020 Biomarker disease BEFREE Based on our previous finding that protease-activated receptor 2 (PAR-2) regulates hemophagocytosis of oral squamous cell carcinoma (SCC) cells, which induces their heme oxygenase 1-dependent keratinization, we have formulated a hypothesis that PAR-2 functions in wider activities of SCC cells. 25912757 2015
CUI: C0876991
Disease: Histiocytosis haematophagic
Histiocytosis haematophagic 		0.020 AlteredExpression disease BEFREE Immunofluorescence signals for K10, K17, and HO-1 were enhanced due to hemophagocytosis in time-dependent manners. mRNA expression levels for the three molecules were most enhanced by purified Hb, followed by crude Hb and erythrocytes. 23526486 2013