FOXA1, forkhead box A1, 3169

N. diseases: 138; N. variants: 1
Disease: Pancreatic carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.020 Biomarker disease BEFREE Acquired molecular changes can promote the spreading of primary tumor cells to distant tissues.In this issue of Cell, Roe et al. show that metastatic progression of pancreatic cancer involves large-scale enhancer reprogramming by Foxa1, which activates transcriptional program specifying early endodermal stem cells. 28841414 2017
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.020 Biomarker disease BEFREE Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer. 20160041 2010