Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.030 Biomarker group BEFREE As expected, Apaf-1 was detected in the cytosolic fractions of non-B cell lymphomas and non-cancerous tissues; however, in B cell derived lymphomas the protein was detected in membrane raft sub-domains rather than the cytosol. 27863378 2016
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.030 Biomarker group LHGDN Together, our findings suggest that ectopic (noncytosolic) localization of Apaf-1 may constitute a novel mechanism of chemoresistance in B lymphoma. 15692060 2005
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.030 Biomarker group BEFREE Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance. 15692060 2005
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.030 Biomarker group BEFREE Therefore, cDNAs coding for Apaf-1 were examined in six lymphoma derived cell lines, in three non-lymphoid tumor cell lines, as well as in peripheral blood lymphocytes and in tissue from heart, kidney, and liver by RT-PCR. 10441496 1999