FOXA2, forkhead box A2, 3170

N. diseases: 143; N. variants: 1
Disease: Biliary Atresia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.030 Biomarker disease BEFREE A strong significant statistical difference between BA and NC group (P<0.0001) with regard to Hnf1β and FoxA2 immunoexpression was evident. 29406331 2019
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.030 AlteredExpression disease BEFREE As FOXA2 can be a regulator of NODAL expression, we propose that haploinsufficiency for FOXA2 combined with a decreased expression of NODAL is the likely cause for syndromic BA in this proband. 25765999 2015
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.030 AlteredExpression disease BEFREE Expression of IL-6, Foxa2, and phosphorylated signal transducer activator of transcription 3 (STAT3) was investigated in patients with biliary atresia (BA) and in rats subjected to bile duct ligation (BDL). miRNA expression was determined in BA patients and BDL rats, with miRNA array and quantitative real-time PCR. 25450715 2015