ONECUT1, one cut homeobox 1, 3175

N. diseases: 36; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 AlteredExpression phenotype BEFREE Hepatocyte nuclear factor 6 (HNF6), as a transcription factor, has been reported to be involved in cell proliferation, carcinogenesis, and tumor metastasis. 30256389 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 Biomarker phenotype BEFREE This study sought to investigate the role of HNF6, particularly the molecular mechanisms for how HNF6 is involved in the growth and metastasis of cholangiocarcinoma (CCA) cells. 26825606 2016
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 Biomarker phenotype LHGDN For its known interaction with HNF6, we investigated expression of FOXA2, which we found to be specifically induced in colorectal liver metastases. 17283222 2007