HOXA10, homeobox A10, 3206

N. diseases: 122; N. variants: 5
Disease: Malignant neoplasm of stomach ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 Biomarker disease BEFREE Therefore, the current study was performed to explore the role and mechanism of HOXA10 in gastric cancer. 31406476 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE In summary, our study indicated that HOXA10 was upregulated in GC, and that HOXA10 might promote cell proliferation by elevating BCL2 expression and inhibiting apoptosis. 31364281 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 PosttranslationalModification disease BEFREE Functionally, miR-196b-5p reconstitution promoted human gastric cancer cell proliferation and invasion <i>in vitro</i> In summary, the current data demonstrate overexpression of miR-196b-5p in gastric cancer and suggest that TFF1 plays an important role in suppressing the expression of miR-196b-5p by mediating DNA methylation of the HOXA10 promoter. 29453320 2018
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 Biomarker disease BEFREE HOXA10(+)/CD44(+) expression might serve as a prognostic biomarker for GC, which needs more studies to validate. 26552644 2015
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 Biomarker disease BEFREE Expression of CDH17, REG4, HOXA10 and DSC2 and downregulation of CLDN18 are observed in the intestinal phenotype of GC. 26033320 2015
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE Co-activation of miR-196b and HOXA10 characterized a poor-prognosis subgroup of patients with gastric cancer. 24222951 2013
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE HOXA10 expression was associated with GC with the intestinal mucin phenotype and correlated with CDX2 expression. 22411957 2012
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE Expression of SOX9, HOXA10, CDH17, and loss of claudin-18 expression were associated with an intestinal phenotype of gastric cancer. 19261089 2009