HOXB7, homeobox B7, 3217

N. diseases: 93; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE Therefore, the present results identified that HOXB7 could play a critical role in carcinogenesis, and may serve as a therapeutic target for the treatment of osteosarcoma. 28677742 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE Homeobox B7 (HOXB7), a member of the HOX gene family, plays a role in tumorigenesis. 27983923 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE Dysregulation of homeobox B7 (HOXB7), a member of the homeobox genes family, was suggested to play a role in regulation of tumorigenesis and metastases of some cancers. 22911672 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 AlteredExpression phenotype BEFREE The homeobox gene HOXB7 is overexpressed across a range of cancers and promotes tumorigenesis through varying effects on proliferation, survival, invasion, and angiogenesis. 22914903 2013
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE Conversely, knockdown of HOXB7 caused an inhibition of cell growth, proliferation, and tumorigenesis. 21474578 2011