HOXB7, homeobox B7, 3217

N. diseases: 93; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.030 Biomarker disease BEFREE <b>Aim:</b> To study the carcinogenetic mechanism of HOXB7 in gastric cancer (GC) remains. 31190875 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.030 AlteredExpression disease BEFREE In conclusion, our results showed that increased expression of HOXB7 might play an important role in promoting GC proliferation, migration and invasion by inducing both AKT and MAPK pathways, thus resulting in progression of, and poor prognosis in GC patients. 27901487 2017
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.030 Biomarker disease BEFREE Our study suggests that HOXB7 has an oncogenic role in gastric cancer, which might be related to the modulation of Akt/PTEN activity to induce cell migration/invasion and anti-apoptotic effects. 26968988 2016